The 2012 E350 uses a 3.5-liter V6 gasoline engine (Mercedes M272) that produces about 268 horsepower and 258 lb-ft of torque, paired with a seven-speed automatic transmission.
In this article, we break down the engine type, its key specifications, performance characteristics, and how to verify the exact engine in your vehicle.
Engine specifications
Core data
Below are the core figures you’ll typically find for the 2012 E350 in most markets:
- Engine type: 3.5-liter V6 gasoline
- Engine code: M272
- Displacement: 3,498 cc
- Power output: 268 horsepower (approximately)
- Torque: 258 lb-ft (approximately 350 Nm)
- Configuration: 60-degree V6
Note: Some markets may show minor variations, but the 3.5L V6 M272 configuration is standard for the E350 in 2012.
Performance and transmission
Drivetrain details
The engine is paired with Mercedes’ seven-speed automatic transmission (7G-Tronic), delivering smooth shifts and steady acceleration. In the 2012 E-Class lineup, the base E350 commonly offered rear-wheel drive with a 4MATIC all-wheel-drive option available in some markets.
- Transmission: 7-speed automatic (7G-Tronic)
- Drivetrain options: Rear-wheel drive standard; 4MATIC all-wheel drive available in certain markets
- Power delivery: Smooth, refined downshifts and ample mid-range torque
Together, the 3.5L V6 and 7G-Tronic transmission aim to balance comfort with responsive on-road performance, consistent with the E-Class philosophy for that model year.
Verification and variations
How to confirm your exact engine
Because Mercedes-Benz offered regional options and occasional trims that could influence the engine setup, it’s best to confirm the engine code on your specific car. Look for the M272 engine code on the engine cover or on a stamping on the engine block, and cross-check with your vehicle’s VIN and documentation. This will confirm you’re looking at the standard 3.5-liter V6 used in the 2012 E350 for that market.
- Engine code: M272
- Displacement: 3.5 L
Verifying these details ensures you’re referencing the exact engine configuration for your particular vehicle.
Summary
In short, the 2012 Mercedes-Benz E350 is powered by a 3.5-liter V6 gasoline engine (M272) delivering roughly 268 horsepower and 258 lb-ft of torque, paired with a seven-speed automatic transmission. Depending on the market, rear-wheel drive is standard with an optional 4MATIC all-wheel drive. For exact specifications on a specific car, verify the engine code (M272) via the engine block or vehicle VIN documentation.


