The official OEM oil filter for a 2008 Lexus RX 350 is 04152-YZZA6. This applies to the 3.5-liter V6 engine (2GR-FE) used in that model year. When purchasing, ensure the filter is the cartridge-style designed for the 2GR-FE to guarantee proper fit and filtration. It's prudent to verify against your VIN or the official Lexus/Toyota parts catalog, as regional revisions can occur.
What engine and filter type does the RX 350 use?
The 2008 RX 350 runs the 3.5L V6 engine code 2GR-FE, which uses a cartridge-style oil filter. The 04152-YZZA6 part is the OEM filter designed to fit the 2GR-FE installation, and it is a widely used standard for this engine across several Toyota and Lexus models from roughly the mid-2000s onward.
Official part number and cross-compatibility
The Lexus/Toyota parts catalog commonly lists 04152-YZZA6 as the OEM oil filter for the 2008 RX 350 with the 2GR-FE engine. While some aftermarket retailers may offer cross-reference numbers, using the OEM code ensures the correct fit and filtration performance for that engine family.
How to verify compatibility
VIN-based confirmation
To confirm the exact part for your vehicle, enter your VIN on the Lexus Parts catalog, a Toyota dealer portal, or a trusted aftermarket retailer. This ensures any regional revision or update is accounted for.
Dealer and retailer checks
When shopping, you can also ask a parts specialist to look up the 2GR-FE oil filter by model year, engine, and VIN to confirm the correct code before purchase.
Where to buy
OEM oil filters are available through Lexus and Toyota dealers, authorized parts retailers, and major aftermarket suppliers. If you’re substituting with an aftermarket filter, ensure it matches the OEM specification (size, thread, and cartridge design) for the 2GR-FE engine.
Summary
For a 2008 Lexus RX 350 with the 3.5L 2GR-FE engine, the OEM oil filter part number is 04152-YZZA6. Always verify with your VIN and use the official parts catalog or a trusted dealer to confirm the exact part revision before purchasing.


