The oil filter on a 2010 Lexus RX 350 is located inside a cylindrical housing mounted to the engine block; it uses a cartridge inside a canister rather than a traditional spin-on filter. It’s typically found on the engine’s side, toward the passenger side of the engine bay, and can be accessed with the hood up.
In more detail, the RX 350’s 3.5-liter V6 (2GR-FE) employs a cartridge-style oil filter inside a round canister. Service involves removing the canister cap to swap in a new cartridge and O-ring, then resealing. Access may require moving aside wiring or shielding for clearance, and you should follow proper procedures to prevent leaks or oil contamination.
Where to look in the engine bay
The filter is not a visible spin-on under the car. Instead, look for a round, black oil filter housing attached to the engine block. It sits toward the side of the engine (commonly the passenger side front area) and is connected to the oil passages. The canister cap is what you remove to access the inner cartridge.
How to locate and service the filter
Here are the essential steps you’ll follow to locate and service the oil filter on this model.
- Warm up the engine, park on a level surface, engage the parking brake, and place wheel chocks as needed.
- Open the hood and remove the engine oil fill cap to vent pressure, then position a drain pan beneath the oil pan.
- Locate the round oil filter housing on the side of the engine block—the canister with the cap on top.
- Use the appropriate socket or strap wrench to loosen and remove the cap from the canister. Carefully extract the old cartridge and inspect the housing for debris.
- Install the new cartridge into the housing, then fit a new O-ring on the cap. Lightly lubricate the O-ring with fresh engine oil.
- Reinstall the cap securely and wipe away any spilled oil. Refill the engine with the correct oil type and amount to the proper level.
- Start the engine, check for leaks around the filter cap, and recheck the oil level after a brief idle. Top off if necessary.
Note: If access is hindered by shielding or other components, consult the owner’s manual or a Lexus service manual for your exact VIN, or have a qualified technician perform the change to avoid leaks or damage.
Summary
For the 2010 Lexus RX 350, the oil filter is a cartridge inside a cylindrical housing mounted to the engine block on the side of the engine bay. Replacement involves removing the cap, swapping the cartridge, replacing the O-ring, and rechecking the oil level. When in doubt, consult the manual or a professional to ensure proper installation and sealing.


