The engine most commonly found in Ford E-350 motorhomes is the 6.8-liter Triton V10 gasoline engine. Some older builds or diesel-equipped versions may use a 5.4-liter V8 or the 6.0-liter Power Stroke diesel.
The Ford E-350 is a cutaway chassis used by many Class C motorhomes. Engine options have varied with model year and configuration. Today’s gasoline-powered E-350 motorhomes typically rely on the 6.8L V10, while earlier years and certain diesel configurations used alternative engines. Reading the manufacturer’s build sheet is the best way to know the exact powerplant for a given unit.
Common engine options on Ford E-350 motorhomes
Engine options are typically categorized by fuel type. The following list highlights the engines most commonly encountered on E-350 motorhomes, separated into gasoline and diesel options.
- Gasoline engines
- 6.8-liter Triton V10 (the standard choice for many late-model E-350 motorhomes)
- 5.4-liter Triton V8 (older builds and early generations)
- Diesel engines
- 6.0-liter Power Stroke V8 diesel (found on some diesel-equipped E-350/E-450 cutaways in certain years)
Overall, the gasoline route—primarily the 6.8L V10—poses the most common configuration for modern E-350 motorhomes, with older gas engines and some diesel options appearing in earlier builds or specialty conversions.
Gasoline vs Diesel considerations
Choosing between gasoline and diesel impacts power delivery, maintenance, fuel economy, and operating costs. Gasoline V10s are generally simpler to service and have lower upfront costs, while diesel engines offer greater torque for towing or climbing grades but come with higher maintenance and fuel prices.
- Fuel economy and range considerations
- Maintenance costs and parts availability
- Torque and towing requirements
In practice, for most recreational use, the 6.8L V10 gasoline engine provides a solid balance of power, reliability, and ease of repair. Diesel chassis remain preferred by some long-distance travelers or those routinely hauling heavy loads.
Summary
Ford E-350 motorhomes are typically powered by a 6.8-liter Triton V10 gasoline engine, with older builds using a 5.4-liter V8 or a 6.0-liter Power Stroke diesel. To confirm the exact engine in a specific unit, check the chassis build sheet or the RV’s documentation from the manufacturer.


