The 2010 Lexus IS 250 uses a standard spin‑on oil filter designed for its 2.5-liter V6. The factory (OEM) filter part number is 04152-YZZA1, and many aftermarket options are cross‑compatible when they match the same engine specifications and mounting dimensions.
The IS 250 from 2010 relies on a 2.5-liter V6 engine, commonly equipped with Toyota/Lexus filtration components tuned to fit a range of 2.5L engines in the brand family. Replacing the filter during oil changes is a routine maintenance item intended to ensure proper oil flow and filtration for the engine’s longevity.
OEM oil filter for the 2010 IS 250
The following part reflects the factory recommendation for this model.
- 04152-YZZA1
Using the OEM filter ensures a guaranteed fit and compatibility with the IS 250’s 2.5L engine design and oil system.
Aftermarket cross-reference and compatibility
If you prefer aftermarket options, use filters that explicitly list compatibility with Toyota/Lexus 2.5L engines (including the IS 250). When evaluating options, verify the filter’s specifications match the vehicle’s thread size and gasket design, and confirm fitment for the 2010 IS 250 engine family.
- Choose filters that state explicit compatibility with Toyota/Lexus 2.5L engines and the IS 250.
- Verify the filter’s thread size and gasket type match the engine’s requirements; improper fit can lead to leaks or poor filtration.
- Check the filter’s overall dimensions (diameter and height) to ensure it clears nearby components during installation.
- Consult the retailer’s cross-reference chart or the filter manufacturer’s compatibility guide if you’re unsure.
In practice, many reputable aftermarket filters will be labeled as compatible with the 2.5L Lexus/Toyota engines; ensure the packaging or product page confirms fitment for the 2010 IS 250.
Practical tips for choosing and replacing the filter
Always verify the vehicle’s exact engine and market, as there can be regional variations. When in doubt, sticking with the OEM 04152-YZZA1 is the safest choice for fit and filtration performance. If you replace with an aftermarket option, follow the manufacturer’s installation instructions and replace the oil filter along with a fresh oil change using the recommended oil grade and viscosity.
Summary: For a 2010 Lexus IS 250, the OEM oil filter is 04152-YZZA1, and aftermarket options are available as long as they are explicitly compatible with Toyota/Lexus 2.5L engines and fit the IS 250’s mounting specifications. Always confirm fitment with your VIN or retailer if you’re unsure.


