The official oil filter for a 2010 Lexus RX 350 is part number 04152-YZZA1.
This article explains the exact part number, how it fits the 3.5-liter V6 (2GR-FE) engine in the 2010 RX 350, and how to verify compatibility with aftermarket options.
Part number and exact fit
Identify the correct filter by using the OEM Lexus/Toyota designation and the model year and engine code for the RX 350.
OEM part number
The standard oil filter for the 3.5L V6 in the 2010 RX 350 is 04152-YZZA1. This number is used by Lexus and Toyota dealers for this model and year.
Before you buy, confirm the number matches your vehicle’s VIN or regional catalog, as some markets use slight suffix changes.
- 04152-YZZA1 — Lexus/Toyota OEM oil filter for the 2010 RX 350 (3.5L V6, 2GR-FE).
Using the OEM part ensures compatibility and the expected sealing and filtering performance.
Aftermarket cross-references
Many buyers opt for reputable aftermarket filters that cross-reference to 04152-YZZA1. When shopping for a substitute, ensure the filter is marketed as compatible with the 3.5L V6 RX 350 and verify with the retailer’s cross-reference tool.
- Cross-reference approach: Look up 04152-YZZA1 in the brand’s cross-reference guide (e.g., Wix, Bosch, Fram, K&N) to find the equivalent filter number for their product line.
Always confirm fit by engine code (2GR-FE) and model year (2010 RX 350) to avoid incorrect installation.
How to replace the oil filter (brief guide)
Prepare with a new oil filter, a new sealing O-ring if provided, and the correct grade and amount of engine oil. Drain the old oil, remove the old filter, install the new filter by hand until snug (do not over-tighten), lubricate the new O-ring, and refill with the recommended oil capacity as specified in the owner’s manual. Check for leaks after starting the engine and recheck oil level.
Summary
For a 2010 Lexus RX 350, the oil filter part number is 04152-YZZA1. This OEM designation matches the 3.5L V6 (2GR-FE) engine used in that model year. You can source this exact part from Lexus dealers or auto parts retailers, and you can also use aftermarket cross-references that map to 04152-YZZA1. Always verify fit via VIN and manufacturer guidance to ensure proper compatibility.