The 2016 Honda Odyssey’s gas mileage depends on drivetrain. Front-wheel-drive (FWD) models typically achieve about 19 mpg in the city, 28 mpg on the highway, and around 22 mpg combined. All-wheel-drive (AWD) versions are slightly less efficient, generally around 18 mpg city, 27 mpg highway, and about 21 mpg combined.
These figures come from EPA estimates for the model’s 3.5-liter V6 engine paired with a six-speed automatic transmission and are intended as a guide. Real-world mileage varies with driving conditions, load, trim level, and maintenance.
EPA fuel economy by drivetrain
The following figures are EPA estimates for the 2016 Odyssey, representing typical configurations with the 3.5L V6 and automatic transmission.
- Front-Wheel Drive (FWD): 19 mpg city / 28 mpg highway / 22 mpg combined
- All-Wheel Drive (AWD): 18 mpg city / 27 mpg highway / 21 mpg combined
Real-world mileage can differ based on factors such as driving style, traffic conditions, load, tire quality, and climate control usage.
Summary
For the 2016 Honda Odyssey, EPA estimates indicate 19/28/22 mpg (FWD) and 18/27/21 mpg (AWD). These figures provide a baseline, but actual fuel economy will vary with how you drive, how heavily you load the vehicle, and how well it’s maintained.